Thanks to recent technical advances, cryo-electron microscopy or cryo-EM, is increasingly positioned as a key solution within the field of structural biology. Cryo-EM is capable of quickly generating high-resolution models of small and large protein complexes, without having to first crystallize the protein. Furthermore, these technical improvements have triggered a “resolution revolution” in the domain of single particle analysis (SPA), and has allowed the technique to routinely achieve sub-nanometer resolution imaging of proteins. These advances have the potential to open a vast range of important biological problems that have remained out of reach with traditional techniques.
The steady adoption of cryo-EM SPA has generated a growing demand for highly reliable, fast and robust acquisition technologies. In this webcast, we introduce the new Thermo Scientific™ Krios™ G3i and the Thermo Scientific™ Glacios™ cryo-transmission electron microscopes, which represent the most economical and efficient cryo-EM solutions available for acquiring the 3D structure of molecules. We discuss their advantages and applications in cryo-EM single particle analysis.
In this webcast we address:
